click on (…) then Downloads and updates, here look for if any updates available and install them. If you have installed iTunes from Windows 10 store simple open Microsoft store. However, updating it to the latest version of iTunes may fix such issues. Windows 10 receives frequent automatic updates on a regular basis and this may cause enough changes so as to prevent iTunes from running properly. Under the Compatibility tab, check the box next to Run This Program in Compatibility Mode.Right-click on the iTunes shortcut icon, and select Properties.To do this simply right-click on the iTunes shortcut icon and select run as administrator. If you notice iTunes not working smoothly on your Windows 10 PC/Laptop then first try to run the application with administrative privileges which allow it to bypass such restrictions and open up as usual. iTunes not working smoothly in windows 10 Select each of them and choose Uninstall and once you finish, restart your computer And try to run the latest iTunes setup which may resolve the issue.

Apple Application Support (both 64 and 32 bit).

Uninstall any old version of Apple programs at your Programs and Features page in your Control Panel:

Itunes does not install on windows 10